Anisodamin

Anisodamin
(IUPAC) ime
	[(1S,3S,5S,7S)-7-Hidroksi-8-metil-8-azabiciklo[3.2.1]oktan-3-il] (2S)-3-hidroksi-2-fenil-propanoat
Klinički podaci
Identifikatori
CAS broj	55869-99-3
ATC kod	nije dodeljen
PubChem	183088
ChemSpider	159209
UNII	01343Q8EL8
Hemijski podaci
Formula	C17H23NO4
Mol. masa	305,37 g/mol
SMILES	eMolekuli & PubHem
InChI
	InChI=1S/C17H23NO4/c1-18-12-7-13(9-15(18)16(20)8-12)22-17(21)14(10-19)11-5-3-2-4-6-11/h2-6,12-16,19-20H,7-10H2,1H3/t12-,13+,14-,15+,16+/m1/s1 ; Key: WTQYWNWRJNXDEG-LEOABGAYSA-N
Farmakoinformacioni podaci
Trudnoća	?
Pravni status

Anisodamin (7β-hidroksihiosciamin) je antiholinergik i antagonist α₁-adrenergičkog receptora koji se koristi za tretiranje akutnog cirkulatornog šoka i Kini.^[4] On je isto tako prirodni tropanski alkaloid koji je prisutan u pojedinim biljkama iz Solanaceae familije.^[5]

Reference

↑ Li Q, Cheng T, Wang Y, Bryant SH (2010). „PubChem as a public resource for drug discovery.”. Drug Discov Today 15 (23-24): 1052-7. DOI:10.1016/j.drudis.2010.10.003. PMID 20970519. edit
↑ Evan E. Bolton, Yanli Wang, Paul A. Thiessen, Stephen H. Bryant (2008). „Chapter 12 PubChem: Integrated Platform of Small Molecules and Biological Activities”. Annual Reports in Computational Chemistry 4: 217-241. DOI:10.1016/S1574-1400(08)00012-1.
↑ Hettne KM, Williams AJ, van Mulligen EM, Kleinjans J, Tkachenko V, Kors JA. (2010). „Automatic vs. manual curation of a multi-source chemical dictionary: the impact on text mining”. J Cheminform 2 (1): 3. DOI:10.1186/1758-2946-2-3. PMID 20331846. edit
↑ Varma DR, Yue TL (March 1986). „Adrenoceptor blocking properties of atropine-like agents anisodamine and anisodine on brain and cardiovascular tissues of rats”. British Journal of Pharmacology 87 (3): 587–94. PMC 1916562. PMID 2879586.
↑ Zhang WW, Song MK, Cui YY, et al. (October 2008). „Differential neuropsychopharmacological influences of naturally occurring tropane alkaloids anisodamine versus scopolamine”. Neuroscience Letters 443 (3): 241–5. DOI:10.1016/j.neulet.2008.07.048. PMID 18672024.

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