Membrane cofactor protein

CD46
Identifiers
Aliases	CD46, AHUS2, MCP, MIC10, TLX, TRA2.10, CD46 molecule
External IDs	OMIM: 120920; MGI: 1203290; GeneCards: CD46
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 3O8E, 1CKL, 2O39, 3INB, 3L89, 5FO8
Gene location (Human) Chr. Chromosome 1 (human) Band 1q32.2 Start 207,752,037 bp End 207,795,513 bp
Gene location (Mouse) Chr. Chromosome 1 (mouse) Band 1 H6|1 98.41 cM Start 194,719,134 bp End 194,774,557 bp
RNA expression pattern Bgee Human Mouse (ortholog) Top expressed in palpebral conjunctiva seminal vesicula bronchial epithelial cell jejunal mucosa germinal epithelium parotid gland placenta right uterine tube right lung body of pancreas Top expressed in seminiferous tubule spermatid granulocyte vastus lateralis muscle intestinal villus primary visual cortex lumbar subsegment of spinal cord muscle of thigh ventricular zone embryo More reference expression data BioGPS More reference expression data
Gene ontology Molecular function virus receptor activity cadherin binding protein binding complement binding endopeptidase activity enzyme inhibitor activity signaling receptor activity Cellular component integral component of membrane inner acrosomal membrane membrane focal adhesion plasma membrane integral component of plasma membrane cell surface extracellular exosome cytoplasmic vesicle acrosomal vesicle cytoplasm Golgi apparatus basolateral plasma membrane Biological process T cell mediated immunity adaptive immune response positive regulation of interleukin-10 production immune system process