MAGT1

MAGT1
Identifikatori
Aliasi	MAGT1
Vanjski ID-jevi	OMIM: 300715 MGI: 1914325 HomoloGene: 100678 GeneCards: MAGT1
Lokacija gena (čovjek) Hrom. Hromosom X Bend Xq21.1 Početak 77,825,747 bp Kraj 77,899,271 bp
Lokacija gena (miš) Hrom. Hromosom X (miš) Bend X|X D Početak 105,011,690 bp Kraj 105,055,512 bp
Obrazac RNK ekspresije Više referentnih podataka o ekspresiji
Ontologija gena Molekularna funkcija • magnesium ion transmembrane transporter activity • dolichyl-diphosphooligosaccharide-protein glycotransferase activity Ćelijska komponenta • integral component of membrane • oligosaccharyltransferase complex • ćelijska membrana • integral component of plasma membrane • membrana • endoplasmic reticulum membrane • azurophil granule membrane • Endoplazmatski retikulum Biološki proces • magnesium ion transport • protein N-linked glycosylation • kognitivna funkcija • transmembrane transport • magnesium ion transmembrane transport • neutrophil degranulation • GO:0033578, GO:0033577, GO:0033575, GO:0033576 protein glycosylation • protein N-linked glycosylation via asparagine • GO:0015915 transport Izvori:Amigo / QuickGO
Ortolozi
Vrste	Čovjek	Miš
Entrez	84061	67075
Ensembl	ENSG00000102158	ENSMUSG00000031232
UniProt	Q9H0U3	Q9CQY5
RefSeq (mRNK)	NM_032121 NM_001367916	NM_001190409 NM_025952 NM_001377002 NM_001377003
RefSeq (bjelančevina)	NP_115497 NP_001354845	NP_001177338 NP_080228 NP_001363931 NP_001363932
Lokacija (UCSC)	Chr X: 77.83 – 77.9 Mb	Chr X: 105.01 – 105.06 Mb
PubMed pretraga
Wikipodaci
Pogledaj/uredi – čovjek Pogledaj/uredi – miš

Magnezijski transportni protein 1 je protein koji je kod ljudi kodiran genom MAGT1.

Funkcije ortologa

Molekulska funkcija • aktivnost transmembranskog transportera magnezijevih iona

• aktivnost glikotransferaze dolihil-difosfooligosaccharid-protein

Ćelijska komponenta • integralna komponenta membrane

• kompleks oligosahariltransferaze • ćelijska membrane • integralna komponenta plazmatske membrane • membrana • membrana endoplazmatskog retikuluma • membrana azurofilnih granula • endoplazmatski retikulum

Biološki proces • transport magnezijumovih jona • proteinska N-vezana glikozilacija • transmembranski transport • transmembranski transport magnezijevih iona • degranulacija neutrofila • glikozilacija proteina • proteinska N-vezana glikozilacija preko asparagina • transport

Izvori: Amigo / QuickGO

Molekulska funkcija • aktivnost transmembranskog transportera magnezijskih iona

• aktivnost glikotransferaze dolihil-difosfooligosaccharid-proteina

Ćelijska komponenta • integralna komponenta membrane

• kompleks oligosahariltransferaze • ćelijske membrane • integralna komponenta plazmatske membrane • membrana • membrana endoplazmatskog retikuluma • membrana azurofilnih granula • endoplazmatski retikulum

Biološki proces • transport magnezijskih iona

• proteinska N-vezana glikozilacija • transmembranski transport • transmembranski transport magnezijevih iona • degranulacija neutrofila • glikozilacija proteina • proteinska N-vezana glikozilacija preko asparagina • transport

Izvori: Amigo/QuickGO

Dopunska literatura

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• Kelleher DJ, Karaoglu D, Mandon EC, Gilmore R (2003). "Oligosaccharyltransferase isoforms that contain different catalytic STT3 subunits have distinct enzymatic properties". Mol. Cell. 12 (1): 101–11. doi:10.1016/S1097-2765(03)00243-0. PMID 12887896.
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• Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
• Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
• Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
• Shibatani T, David LL, McCormack AL, et al. (2005). "Proteomic analysis of mammalian oligosaccharyltransferase reveals multiple subcomplexes that contain Sec61, TRAP, and two potential new subunits". Biochemistry. 44 (16): 5982–92. doi:10.1021/bi047328f. PMID 15835887.
• Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.