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Computer Science > Computer Vision and Pattern Recognition

arXiv:2303.00915 (cs)
[Submitted on 2 Mar 2023 (v1), last revised 8 Jan 2025 (this version, v3)]

Title:BiomedCLIP: a multimodal biomedical foundation model pretrained from fifteen million scientific image-text pairs

Authors:Sheng Zhang, Yanbo Xu, Naoto Usuyama, Hanwen Xu, Jaspreet Bagga, Robert Tinn, Sam Preston, Rajesh Rao, Mu Wei, Naveen Valluri, Cliff Wong, Andrea Tupini, Yu Wang, Matt Mazzola, Swadheen Shukla, Lars Liden, Jianfeng Gao, Angela Crabtree, Brian Piening, Carlo Bifulco, Matthew P. Lungren, Tristan Naumann, Sheng Wang, Hoifung Poon
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Abstract:Biomedical data is inherently multimodal, comprising physical measurements and natural language narratives. A generalist biomedical AI model needs to simultaneously process different modalities of data, including text and images. Therefore, training an effective generalist biomedical model requires high-quality multimodal data, such as parallel image-text pairs. Here, we present PMC-15M, a novel dataset that is two orders of magnitude larger than existing biomedical multimodal datasets such as MIMIC-CXR, and spans a diverse range of biomedical image types. PMC-15M contains 15 million biomedical image-text pairs collected from 4.4 million scientific articles. Based on PMC-15M, we have pretrained BiomedCLIP, a multimodal foundation model, with domain-specific adaptations tailored to biomedical vision-language processing. We conducted extensive experiments and ablation studies on standard biomedical imaging tasks from retrieval to classification to visual question-answering (VQA). BiomedCLIP achieved new state-of-the-art results in a wide range of standard datasets, substantially outperforming prior approaches. Intriguingly, by large-scale pretraining on diverse biomedical image types, BiomedCLIP even outperforms state-of-the-art radiology-specific models such as BioViL in radiology-specific tasks such as RSNA pneumonia detection. In summary, BiomedCLIP is a fully open-access foundation model that achieves state-of-the-art performance on various biomedical tasks, paving the way for transformative multimodal biomedical discovery and applications. We release our models at this https URL to facilitate future research in multimodal biomedical AI.
Comments: The models are released at this https URL
Subjects: Computer Vision and Pattern Recognition (cs.CV); Computation and Language (cs.CL)
Cite as: arXiv:2303.00915 [cs.CV]
  (or arXiv:2303.00915v3 [cs.CV] for this version)
  https://doi.org/10.48550/arXiv.2303.00915
arXiv-issued DOI via DataCite

Submission history

From: Sheng Zhang [view email]
[v1] Thu, 2 Mar 2023 02:20:04 UTC (714 KB)
[v2] Tue, 16 Jan 2024 21:42:24 UTC (8,889 KB)
[v3] Wed, 8 Jan 2025 22:58:51 UTC (12,598 KB)
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